synthetic lethality

English

Noun

synthetic lethality (usually uncountable, plural synthetic lethalities)

  1. (genetics) A type of genetic interaction in which two (or more) mutations which are not lethal when occurring singly in a cell are lethal when they occur together in the same cell.

References

  • Maloy, Stanley with French-Mischo, Stephanie (16 July 2002) “Synthetic Lethal Mutations”, in Microbial Genetics‎[1], San Diego State University, archived from the original on 13 May 2003
  • Le Meur, Nolwenn with Gentleman, Robert (12 September 2008) “Modeling synthetic lethality”, in Genome Biology‎[2], volume 9, →DOI, archived from the original on 14 October 2012, page R135
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