what's up with

• whassup wit, wazzup wit, etc. (nonstandard spellings)

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what's up with

1. (colloquial, in rhetorical questions or salutations) What's wrong with; what's the problem or matter with. Said to express that the behaviour of someone, or operation of something, is out of the ordinary or problematic.

   What’s up with you?

   What the hell's up with this stupid computer now?!

2. (colloquial, in rhetorical questions) Used to express disbelief or curiosity.

   They raised my electricity rates again. What’s up with that?

   What’s up with all this new music they’re playing?

3. (colloquial, in statements) (The thing that is) the problem or issue with.

   I'll tell you what's up with the Government!

• what's with
• what's the deal with
• what's the matter with
• what's the story with
• what's eating (followed by a person's name)

• what gives
• what's cooking
• what's up

• “what's up with”, in OneLook Dictionary Search.